The mission of the Aging Institute is to understand how and why we age and to leverage this information for new therapies to treat age-related diseases.

Zhu Lab

Bokai Zhu, PhD
Assistant Professor of Medicine
Division of Endocrinology and Metabolism

The Zhu lab is studying the role of dynamic proteostasis in the regulation of metabolism and aging, with a focus on the 12h ultradian clock.

Sekine Lab

Yusuke Sekine, PhD
Assistant Professor of Medicine
Division of Endocrinology and Metabolism

Our lab is interested in the molecular mechanisms connecting cellular metabolism with organelle function.

Rizzo Lab

Stacey J. Sukoff Rizzo, PhD
Associate Professor of Neurobiology

The Rizzo Lab uses preclinical model systems and translational approaches towards identifying disease and symptom-modifying therapeutics for Alzheimer’s Disease (AD).

Parkhitko Lab

Andrey A Parkhitko, PhD
Assistant Professor of Medicine
Division of Endocrinology and Metabolism

Our lab is interested in how age-dependent metabolic changes can be targeted to extend health- and lifespan.

Gurkar Lab

Aditi Gurkar, PhD
Assistant Professor of Medicine
Division of Geriatric Medicine

The Gurkar lab aims to identify fundamental mechanisms of aging that can potentially lead to novel strategies to delay the rate of ‘biological’ aging.

Liu Lab

Yuan Liu, PhD
Assistant Professor
Division of Pulmonary, Allergy, and Critical Care Medicine

Our lab is interested in small molecule therapeutic development targeting ubiquitin-dependent protein degradation in age-related diseases.

Sekine Lab

Shiori Sekine, PhD
Assistant Professor of Medicine
Division of Cardiology

Our lab is interested in the molecular mechanisms regulating mitochondrial stress responses.

Finkel Lab

Toren Finkel, MD, PhD
G. Nicholas Beckwith III and Dorothy B. Beckwith Endowed Chair of Translational Medicine Distinguished Professor of Medicine

Our lab is interested in the intersection between metabolism, mitochondrial function and aging.

Liu Lab

Shihui Liu, MD, PhD
Associate Professor of Medicine
Division of Infectious Diseases

Our lab is interested in modifying bacterial protein toxins to design and develop novel therapies for infectious diseases, cancer and other age-related diseases.

Chen Lab

Bill Chen, PhD
Professor of Medicine
Division of Pulmonary, Allergy and Critical Care Medicine

The overall interest of my lab is to uncover novel protein degradation pathways and develop therapeutics to target these pathways.

Eisele Lab

Yvonne S. Eisele, PhD
Assistant Professor of Medicine
Division of Cardiology

We study protein aggregation and delineate structure-toxicity relationships in diseases like Alzheimer’s disease and cardiac amyloidosis.

Li Lab

Gang Li, PhD
Assistant Professor of Medicine
Division of Cardiology

Our lab seeks to understand how disease-associated single nucleotide polymorphisms (SNPs) contribute to susceptibility for age-related diseases including cancers, Alzheimer’s and cardiovascular disease.

Steinhauser Lab

Matthew Steinhauser, MD
Associate Professor of Medicine
Division of Cardiology

Our lab is interested in molecular mechanisms of aging-related cardiometabolic diseases.

Tan Lab

Jay Tan, PhD
Assistant Professor of Cell Biology

The Tan lab studies cellular principles of aging and age-related pathology.

Li Lab

Gang Li, PhD
Assistant Professor of Medicine
Division of Cardiology

Our lab seeks to understand how disease-associated single nucleotide polymorphisms (SNPs) contribute to susceptibility for age-related diseases including cancers, Alzheimer’s and cardiovascular disease.

Sekine Lab

Yusuke Sekine, PhD
Assistant Professor of Medicine
Division of Endocrinology and Metabolism

Our lab is interested in the molecular mechanisms connecting cellular metabolism with organelle function.

Eisele Lab

Yvonne S. Eisele, PhD
Assistant Professor of Medicine
Division of Cardiology

We study protein aggregation and delineate structure-toxicity relationships in diseases like Alzheimer’s disease and cardiac amyloidosis.

Steinhauser Lab

Matthew Steinhauser, MD
Associate Professor of Medicine
Division of Cardiology

Our lab is interested in molecular mechanisms of aging-related cardiometabolic diseases.

Finkel Lab

Toren Finkel, MD, PhD
G. Nicholas Beckwith III and Dorothy B. Beckwith Endowed Chair of Translational Medicine Distinguished Professor of Medicine

Our lab is interested in the intersection between metabolism, mitochondrial function and aging.

Tan Lab

Jay Tan, PhD
Assistant Professor of Cell Biology

The Tan lab studies cellular principles of aging and age-related pathology.

Rizzo Lab

Stacey J. Sukoff Rizzo, PhD
Associate Professor of Neurobiology

The Rizzo Lab uses preclinical model systems and translational approaches towards identifying disease and symptom-modifying therapeutics for Alzheimer’s Disease (AD).

Sekine Lab

Shiori Sekine, PhD
Assistant Professor of Medicine
Division of Cardiology

Our lab is interested in the molecular mechanisms regulating mitochondrial stress responses.

Chen Lab

Bill Chen, PhD
Professor of Medicine
Division of Pulmonary, Allergy and Critical Care Medicine

The overall interest of my lab is to uncover novel protein degradation pathways and develop therapeutics to target these pathways.

Gurkar Lab

Aditi Gurkar, PhD
Assistant Professor of Medicine
Division of Geriatric Medicine

The Gurkar lab aims to identify fundamental mechanisms of aging that can potentially lead to novel strategies to delay the rate of ‘biological’ aging.

Zhu Lab

Bokai Zhu, PhD
Assistant Professor of Medicine
Division of Endocrinology and Metabolism

The Zhu lab is studying the role of dynamic proteostasis in the regulation of metabolism and aging, with a focus on the 12h ultradian clock.

Parkhitko Lab

Andrey A Parkhitko, PhD
Assistant Professor of Medicine
Division of Endocrinology and Metabolism

Our lab is interested in how age-dependent metabolic changes can be targeted to extend health- and lifespan.

Liu Lab

Shihui Liu, MD, PhD
Associate Professor of Medicine
Division of Infectious Diseases

Our lab is interested in modifying bacterial protein toxins to design and develop novel therapies for infectious diseases, cancer and other age-related diseases.

NEWS

Anne Newman, MD, MPH, named UPMC Chair in Geroscience

Anne Newman, MD, MPH, named UPMC Chair in Geroscience

A Distinguished Professor of Epidemiology and Medicine, this appointment will support Dr. Newman in her role as Clinical Director of the Aging Institute where she is engaged early stage clinical trials that address the biology of aging.

read more

Postdoc Positions Available

The Aging Institute has a variety of opportunities available for postdoc trainees.  Click the button below to view all opportunities.

EVENTS

13th Annual Research Day

November 9, 2022  //  12:00pm-6:00pm

View Research Day Website

Research Seminar Series

2nd Thursday of the month
4:00 – 5:00 pm

Schedule and Details

View/Download Flyer (Fall 2022 flyer forthcoming)

REGISTER HERE to attend. (link for Fall 2022 forthcoming)

Research In Progress Series

3rd Monday of the month
12:00  – 1:00 pm

Schedule and Details

CHRONOS

   CHRONICLE

The Chronos Chronicle

Click HERE to view the PDF in a new tab, or to download/print.