The mission of the Aging Institute is to understand how and why we age and to leverage this information for new therapies to treat age-related diseases.

Liu Lab

Shihui Liu, MD, PhD
Associate Professor of Medicine
Division of Infectious Diseases

Our lab is interested in modifying bacterial protein toxins to design and develop novel therapies for infectious diseases, cancer and other age-related diseases.

Liu Lab

Yuan Liu, PhD
Assistant Professor
Division of Pulmonary, Allergy, and Critical Care Medicine

Our lab is interested in small molecule therapeutic development targeting ubiquitin-dependent protein degradation in age-related diseases.

Eisele Lab

Yvonne S. Eisele, PhD
Assistant Professor of Medicine
Division of Cardiology

We study protein aggregation and delineate structure-toxicity relationships in diseases like Alzheimer’s disease and cardiac amyloidosis.

Gurkar Lab

Aditi Gurkar, PhD
Assistant Professor of Medicine
Division of Geriatric Medicine

The Gurkar lab aims to identify fundamental mechanisms of aging that can potentially lead to novel strategies to delay the rate of ‘biological’ aging.

Steinhauser Lab

Matthew Steinhauser, MD
Associate Professor of Medicine
Division of Cardiology

Our lab is interested in molecular mechanisms of aging-related cardiometabolic diseases.

Parkhitko Lab

Andrey A Parkhitko, PhD
Assistant Professor of Medicine
Division of Endocrinology and Metabolism

Our lab is interested in how age-dependent metabolic changes can be targeted to extend health- and lifespan.

Chen Lab

Bill Chen, PhD
Professor of Medicine
Division of Pulmonary, Allergy and Critical Care Medicine

The overall interest of my lab is to uncover novel protein degradation pathways and develop therapeutics to target these pathways.

Rizzo Lab

Stacey J. Sukoff Rizzo, PhD
Associate Professor of Neurobiology

The Rizzo Lab uses preclinical model systems and translational approaches towards identifying disease and symptom-modifying therapeutics for Alzheimer’s Disease (AD).

Finkel Lab

Toren Finkel, MD, PhD
G. Nicholas Beckwith III and Dorothy B. Beckwith Endowed Chair of Translational Medicine Distinguished Professor of Medicine

Our lab is interested in the intersection between metabolism, mitochondrial function and aging.

Sekine Lab

Yusuke Sekine, PhD
Assistant Professor of Medicine
Division of Endocrinology and Metabolism

Our lab is interested in the molecular mechanisms connecting cellular metabolism with organelle function.

Sekine Lab

Shiori Sekine, PhD
Assistant Professor of Medicine
Division of Cardiology

Our lab is interested in the molecular mechanisms regulating mitochondrial stress responses.

Zhu Lab

Bokai Zhu, PhD
Assistant Professor of Medicine
Division of Endocrinology and Metabolism

The Zhu lab is studying the role of dynamic proteostasis in the regulation of metabolism and aging, with a focus on the 12h ultradian clock.

Li Lab

Gang Li, PhD
Assistant Professor of Medicine
Division of Cardiology

Our lab seeks to understand how disease-associated single nucleotide polymorphisms (SNPs) contribute to susceptibility for age-related diseases including cancers, Alzheimer’s and cardiovascular disease.

Sekine Lab

Shiori Sekine, PhD
Assistant Professor of Medicine
Division of Cardiology

Our lab is interested in the molecular mechanisms regulating mitochondrial stress responses.

Liu Lab

Shihui Liu, MD, PhD
Associate Professor of Medicine
Division of Infectious Diseases

Our lab is interested in modifying bacterial protein toxins to design and develop novel therapies for infectious diseases, cancer and other age-related diseases.

Steinhauser Lab

Matthew Steinhauser, MD
Associate Professor of Medicine
Division of Cardiology

Our lab is interested in molecular mechanisms of aging-related cardiometabolic diseases.

Eisele Lab

Yvonne S. Eisele, PhD
Assistant Professor of Medicine
Division of Cardiology

We study protein aggregation and delineate structure-toxicity relationships in diseases like Alzheimer’s disease and cardiac amyloidosis.

Rizzo Lab

Stacey J. Sukoff Rizzo, PhD
Associate Professor of Neurobiology

The Rizzo Lab uses preclinical model systems and translational approaches towards identifying disease and symptom-modifying therapeutics for Alzheimer’s Disease (AD).

Chen Lab

Bill Chen, PhD
Professor of Medicine
Division of Pulmonary, Allergy and Critical Care Medicine

The overall interest of my lab is to uncover novel protein degradation pathways and develop therapeutics to target these pathways.

Sekine Lab

Yusuke Sekine, PhD
Assistant Professor of Medicine
Division of Endocrinology and Metabolism

Our lab is interested in the molecular mechanisms connecting cellular metabolism with organelle function.

Zhu Lab

Bokai Zhu, PhD
Assistant Professor of Medicine
Division of Endocrinology and Metabolism

The Zhu lab is studying the role of dynamic proteostasis in the regulation of metabolism and aging, with a focus on the 12h ultradian clock.

Gurkar Lab

Aditi Gurkar, PhD
Assistant Professor of Medicine
Division of Geriatric Medicine

The Gurkar lab aims to identify fundamental mechanisms of aging that can potentially lead to novel strategies to delay the rate of ‘biological’ aging.

Finkel Lab

Toren Finkel, MD, PhD
G. Nicholas Beckwith III and Dorothy B. Beckwith Endowed Chair of Translational Medicine Distinguished Professor of Medicine

Our lab is interested in the intersection between metabolism, mitochondrial function and aging.

Parkhitko Lab

Andrey A Parkhitko, PhD
Assistant Professor of Medicine
Division of Endocrinology and Metabolism

Our lab is interested in how age-dependent metabolic changes can be targeted to extend health- and lifespan.

Liu Lab

Yuan Liu, PhD
Assistant Professor
Division of Pulmonary, Allergy, and Critical Care Medicine

Our lab is interested in small molecule therapeutic development targeting ubiquitin-dependent protein degradation in age-related diseases.

Li Lab

Gang Li, PhD
Assistant Professor of Medicine
Division of Cardiology

Our lab seeks to understand how disease-associated single nucleotide polymorphisms (SNPs) contribute to susceptibility for age-related diseases including cancers, Alzheimer’s and cardiovascular disease.

NEWS

Bill Chen, PhD, identifies drugs that could combat COVID-19 mutations

In a recent Nature Communications article, Dr. Bill Chen's lab discuss how a high-throughput screen could be used to identify FDA-approved compounds that may resist SARS-CoV-2 infection. “I grew up in China and came to the U.S. in 2003, the year of the first SARS...

EVENTS

Research Seminar Series

2nd Thursday of the month
12:00 – 1:00 pm

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Research In Progress Series

3rd Monday of the month
12:00  – 1:00 pm

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CHRONOS

   CHRONICLE

The Chronos Chronicle

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